Immunohematology Reference Laboratory
The American Red Cross Immunohematology Reference Laboratories (IRL) have more than 50 years of experience and world class expertise in red cell antibody identification and antigen typing.
Red Cross provides assistance with routine and complex serological cases, selection of suitable donor units and technical and medical consultation, while following rigorous quality standards and process controls.
Available Products and Services
Auto Immune Causes of Anemia
- Immune hemolytic anemia evaluation: autoimmune or drug-induced*
- Investigation of DAT-negative autoimmune hemolytic anemia*
- Investigation of drug-induced immune hemolytic anemia
Antibodies
- Red blood cell antibody identification:
- Single antibody specificity
- Multiple antibody specificities
- Antibody to high prevalence antigen
- Antibody to low prevalence antigen
- Hemolytic disease of the fetus and newborn
- Interfering therapeutic agents investigation
- Red blood cell autoantibody evaluations:
- Warm reactive autoantibody
- Cold reactive autoantibody
- Paroxysmal cold hemoglobinuria
- Monocyte monolayer assay for determination of potential clinical significance of red blood cell antibodies
Antigen Typing
- Antigen-negative red blood cell components
- Phenotyped matched red blood cell components
- High prevalence antigen negative red blood cell components
- Inventory of red blood cell and platelet components with antigen types predicted by molecular testing
- Antigen typing of samples from transfused patients*
- American Rare Donor Program portal for rare red blood cell components and IgA-deficient plasma products
- ABO discrepancy investigations
Transfusion
- Transfusion reaction investigations
- Red blood cell and platelet compatibility testing services*
- IgA status determination*
Contact the Red Cross
We offer Immunohematology Reference Lab Testing in the regions below.